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Sanofi pbpk software packages
Pbpk Software Packages, supplied by Sanofi, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pbpk+software+packages/pbpk+software+packages/pm26037524-12-0-6
Average 90 stars, based on 1 article reviews
pbpk software packages - by Bioz Stars, 2026-09
90/100 stars

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Article Title: PBPK modeling of irbesartan: incorporation of hepatic uptake.
Article Snippet: Copyrig ABSTRACT: Physiological based pharmacokinetic (PBPK) modeling is now commonly used in drug development to integrate human or animal physiological data in order to predict pharmacokinetic profiles.. The aim of this work was to construct and refine a PBPK model of irbesartan taking into account its active uptake via OATP1B1/B3 in order to predict more accurately its pharmacokinetic profile using Simcyp.. The activity and expression of the human hepatocyte transporters OATP1B1 and OATP1B3 were studied.



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